Bob Duronio, PhD, is Director of the Integrative Program for Biological and Genome Sciences (IBGS), and a UNC Lineberger Comprehensive Cancer Center Member and Professor of Biology and Genetics at UNC-Chapel Hill. The Duronio Lab studies the genetic and epigenetic control of cell cycle progression during animal development.
“One of the most fundamental aspects of animal development is the control of progression through the cell cycle. Without this control there would be no coordination between cell proliferation and the formation of the gross anatomy of an organism. In my laboratory we study how different cell lineages control genome duplication and expression during development. We use genetic, genomic and cell biological approaches in Drosophila to examine how chromatin organization influences DNA replication during S phase, and how the expression of the genes encoding the basic building blocks of chromatin, the histones, is controlled and influenced by a phase-transitioned nuclear body called the histone locus body.”